Modelling mitral valvular dynamics–current trend and future directions

Gao, H. , Qi, N., Feng, L., Ma, X., Danton, M., Berry, C. and Luo, X. (2017) Modelling mitral valvular dynamics–current trend and future directions. International Journal for Numerical Methods in Biomedical Engineering, 33(10), e2858. (doi:10.1002/cnm.2858) (PMID:27935265)

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Abstract

Dysfunction of mitral valve causes morbidity and premature mortality and remains a leading medical problem worldwide. Computational modelling aims to understand the biomechanics of human mitral valve and could lead to the development of new treatment, prevention and diagnosis of mitral valve diseases. Compared with the aortic valve, the mitral valve has been much less studied owing to its highly complex structure and strong interaction with the blood flow and the ventricles. However, the interest in mitral valve modelling is growing, and the sophistication level is increasing with the advanced development of computational technology and imaging tools. This review summarises the state-of-the-art modelling of the mitral valve, including static and dynamics models, models with fluid-structure interaction, and models with the left ventricle interaction. Challenges and future directions are also discussed.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Luo, Professor Xiaoyu and Berry, Professor Colin and Qi, Dr Nan and Gao, Dr Hao and Danton, Mr Mark and Feng, Mr Liuyang
Authors: Gao, H., Qi, N., Feng, L., Ma, X., Danton, M., Berry, C., and Luo, X.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Journal Name:International Journal for Numerical Methods in Biomedical Engineering
Publisher:Wiley
ISSN:2040-7939
ISSN (Online):2040-7947
Published Online:16 February 2017
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in International Journal for Numerical Methods in Biomedical Engineering 33(10):e2858
Publisher Policy:Reproduced under a Creative Commons License

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