McNally, S. and Stein, T. (2016) Overview of mammary gland development: a comparison of mouse and human. In: Martin, F., Stein, T. and Howlin, J. (eds.) Mammary Gland Development: Methods and Protocols. Series: Methods in Molecular Biology, 1501 (1501). Springer: New York, pp. 1-17. ISBN 9781493964734 (doi: 10.1007/978-1-4939-6475-8_1)
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Publisher's URL: http://www.springer.com/gb/book/9781493964734
Abstract
The mouse mammary gland is widely used as a model for human breast cancer and has greatly added to our understanding of the molecular mechanisms involved in breast cancer development and progression. To fully appreciate the validity and limitations of the mouse model, it is essential to be aware of the similarities and also the differences that exist between the mouse mammary gland and the human breast. This introduction therefore describes the parallels and contrasts in mouse mammary gland and human breast morphogenesis from an early embryonic phase through to puberty, adulthood, pregnancy, parturition, and lactation, and finally the regressive stage of involution.
| Item Type: | Book Sections |
|---|---|
| Status: | Published |
| Glasgow Author(s) Enlighten ID: | Stein, Dr Torsten |
| Authors: | McNally, S., and Stein, T. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Publisher: | Springer |
| ISSN: | 1064-3745 |
| ISBN: | 9781493964734 |
| Published Online: | 29 October 2016 |
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