McGarry, D. J. and Olson, M. F. (2016) Coping with loss: cell adaptation to cytoskeleton disruption. Developmental Cell, 39(1), pp. 3-4. (doi: 10.1016/j.devcel.2016.09.020) (PMID:27728780)
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Abstract
Unravelling the role of cytoskeleton regulators may be complicated by adaptations to experimental manipulations. In this issue of Developmental Cell, Cerikan et al. (2016) reveal how acute effects of DOCK6 RhoGEF depletion on RAC1 and CDC42 activation are reversed over time by compensatory mechanisms that re-establish cellular homeostasis.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Olson, Professor Michael |
| Authors: | McGarry, D. J., and Olson, M. F. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Developmental Cell |
| Publisher: | Elsevier |
| ISSN: | 1878-1551 |
| ISSN (Online): | 1878-1551 |
| Published Online: | 10 October 2016 |
| Copyright Holders: | Copyright © 2016 Elsevier Inc. |
| First Published: | First published in Developmental Cell 39(1): 3-4 |
| Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
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