Hughes, C. E. , Benson, R. A. , Bedaj, M. and Maffia, P. (2016) Antigen-presenting cells and antigen presentation in tertiary lymphoid organs. Frontiers in Immunology, 7, 481. (doi: 10.3389/fimmu.2016.00481) (PMID:27872626) (PMCID:PMC5097899)
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Abstract
Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures. In this mini review, we will discuss the role of antigen-presenting cells and mechanisms of antigen presentation in TLOs, summarizing what is currently known about this facet of the formation and function of these tissues as well as identifying questions yet to be addressed.
| Item Type: | Articles |
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| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Benson, Dr Robert and Maffia, Professor Pasquale and Hughes, Dr Catherine |
| Authors: | Hughes, C. E., Benson, R. A., Bedaj, M., and Maffia, P. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Frontiers in Immunology |
| Publisher: | Frontiers Media |
| ISSN: | 1664-3224 |
| ISSN (Online): | 1664-3224 |
| Copyright Holders: | Copyright © 2016 Hughes, Benson, Bedaj and Maffia |
| First Published: | First published in Frontiers in Immunology 7: 481 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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