Diagnosis and management of hereditary pancreatic cancer

Humphris, J. L. and Biankin, A. V. (2016) Diagnosis and management of hereditary pancreatic cancer. In: Pichert, G. and Jacobs, C. (eds.) Rare Hereditary Cancers: Diagnosis and Management. Series: Recent results in cancer research (205). Springer International Publishing: Cham, pp. 61-83. ISBN 9783319299969 (doi:10.1007/978-3-319-29998-3_5)

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Publisher's URL: http://www.springer.com/gb/book/9783319299969


Hereditary pancreatic cancer can be diagnosed through family history and/or a personal history of pancreatitis or clinical features suggesting one of the known pancreatic cancer predisposition syndromes. This chapter describes the currently known hereditary pancreatic cancer predisposition syndromes, including Peutz–Jeghers syndrome, familial atypical multiple mole melanoma, hereditary breast and ovarian cancer, Li–Fraumeni syndrome, hereditary non-polyposis colon cancer and familial adenomatous polyposis. Strategies for genetic testing for hereditary pancreatic cancer and the appropriate options for surveillance and cancer risk reduction are discussed. Finally, ongoing research and future directions in the diagnosis and management of hereditary pancreatic cancer will be considered.

Item Type:Book Sections
Glasgow Author(s) Enlighten ID:Biankin, Professor Andrew
Authors: Humphris, J. L., and Biankin, A. V.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Publisher:Springer International Publishing

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