Sadeghpour, A., Hoghooghi, A., Alizadehsani, Z., Rezaei, M., Aghapour, S. and Haghjoo, M. (2013) Single beat determination of intraventricular systolic dyssynchrony in paitents with atrial fibrillation and systolic dysfunction. Research in Cardiovascular Medicine, 2(2), pp. 85-89. (doi: 10.5812/cardiovascmed.8776) (PMID:25478499) (PMCID:PMC4253764)
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Abstract
Background:: Atrial fibrillation (AF) is the most common clinically significant cardiac arrhythmia. However, diagnosis of intraventricular dyssynchrony in patients with AF is difficult due to beat-to-beat variation. Additionally, evaluation of mechanical dyssynchrony in the traditional method is based on average of 5 to 10 beats, which is exhausting and time consuming. Single-beat evaluation of a beat with equal subsequent cardiac cycles has been proposed as an accurate method in patients with AF. Objectives:: We proposed to evaluate intraventricular mechanical dyssynchrony by measuring time-to-peak systolic velocity between basolateral and basoseptal segments (septum to lateral wall delay) using Tissue Doppler Study (TDI) by two different methods. Materials and Methods:: 31 patient (68 ± 10.3 years) with heart failure (EF < 35%) and AF rhythm, R-R cycle length more than 500 msec were evaluated. We found a target beat in which preceding R-R (R-R1) to pre-preceding R-R (R-R2) ratio was 1(RR1/RR2 = 1) then measured the intraventricular dyssynchrony in that cycle. Intraventricular dyssynchrony was also determined and averaged for 8 consecutive cardiac cycles. The values at RR1/RR2 = 1 were compared with the average of intraventricular dyssynchrony in eight cycles and the relationship between dyssynchrony were evaluated by paired T-test, linear Pearson correlation (r2), linear regression analysis. Results:: The average of dyssynchrony in eight cycles showed a positive correlation with dyssynchrony in target beat RR1/RR2 = 1. Average of dyssynchrony in target beat was 46.77 msec, and average of 8 cycle was = 47.701, (P value = 0.776, Pearson linear correlation 0.769). Conclusions:: Measurement of intraventricular dyssynchromy in basoseptal and basolateral segments in AF and heart failure patients in a single beat with RR1/RR2 = 1 , were very similar to the average value of eight cardiac cycle.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Rezaeihemami, Dr Mohsen |
Authors: | Sadeghpour, A., Hoghooghi, A., Alizadehsani, Z., Rezaei, M., Aghapour, S., and Haghjoo, M. |
College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Health Economics and Health Technology Assessment |
Journal Name: | Research in Cardiovascular Medicine |
Publisher: | Kowsar Publishing |
ISSN: | 2251-9572 |
ISSN (Online): | 2251-9580 |
Copyright Holders: | Copyright © 2013 Kowsar Corp. |
First Published: | First published in Research in Cardiovascular Medicine 2(2): 85-89 |
Publisher Policy: | Reproduced under a Creative Commons License |
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