Psoriatic arthritis: embracing pathogenetic and clinical heterogeneity?

McInnes, I. B. (2016) Psoriatic arthritis: embracing pathogenetic and clinical heterogeneity? Clinical and Experimental Rheumatology, 34(4 S98), pp. 9-11. (PMID:27586796)

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Publisher's URL: http://www.clinexprheumatol.org/abstract.asp?a=10855

Abstract

Psoriatic arthritis (PsA) is a clinically heterogeneous condition of skin, joint, enthesis and bone that provides considerable unmet therapeutic need. Recent treatment advances have offered new opportunities to improve quality of life and long term well being for afflicted patients. It is timely therefore, to consider the underlying heterogeneity inherent in the disease from a pathologic aspect so as to best optimise the choice and order of therapeutic application over time. Herein I will discuss the various contributions made by immune pathways to discrete tissue compartments that in turn might allow a more targeted approach to the management of PsA in which different tissues express variable severity of involvement.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McInnes, Professor Iain
Authors: McInnes, I. B.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Clinical and Experimental Rheumatology
Publisher:Pacini Editore SpA
ISSN:1593-098X

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