Xu, G., Zhao, H., Cooper, J. M. and Reboud, J. (2016) Capillary-based multiplexed isothermal nucleic acid-based test for sexually transmitted diseases in patients. Chemical Communications, 52(82), pp. 12187-12190. (doi: 10.1039/C6CC05679B) (PMID:27722490) (PMCID:PMC5058349)
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Abstract
We demonstrate a multiplexed loop mediated isothermal amplification (LAMP) assay for infectious disease diagnostics, where the analytical process flow of target pathogens genomic DNA is performed manually by moving magnetic beads through a series of plugs in a capillary. Heat is provided by a water bath and the results read by the naked eye, enabling applications in low resource settings.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Cooper, Professor Jonathan and Reboud, Dr Julien and Xu, Mr Gaolian |
| Authors: | Xu, G., Zhao, H., Cooper, J. M., and Reboud, J. |
| College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Journal Name: | Chemical Communications |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1359-7345 |
| ISSN (Online): | 1364-548X |
| Published Online: | 08 September 2016 |
| Copyright Holders: | Copyright © 2016 The Royal Society of Chemistry |
| First Published: | First published in Chemical Communications 52(82): 12187-12190 |
| Publisher Policy: | Reproduced under a Creative Commons License |
| Data DOI: | 10.5525/gla.researchdata.349 |
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