Systemic inflammation: Cancer's long-distance reach to maximize metastasis

Coffelt, S. B. and de Visser, K. E. (2016) Systemic inflammation: Cancer's long-distance reach to maximize metastasis. OncoImmunology, 5(2), e1075694. (doi:10.1080/2162402X.2015.1075694) (PMID:27057449) (PMCID:PMC4801429)

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Abstract

While major improvements have been made in targeting primary tumor growth, metastasis and combating cancer spread remain an enigma. We recently identified a systemic inflammatory cascade involving IL17-producing γδ T cells and neutrophils that advance breast cancer metastasis. These data provide insights into how immune cells promote cancer spread.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Coffelt, Dr Seth
Authors: Coffelt, S. B., and de Visser, K. E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:OncoImmunology
Publisher:Taylor and Francis
ISSN:2162-402X
ISSN (Online):2162-402X
Published Online:17 August 2015
Copyright Holders:Copyright © 2016 Taylor and Francis
First Published:First published in OncoImmunology 5(2):e1075694
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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