Imaging of metabolites using secondary ion mass spectrometry

Armitage, E. G. , Kotze, H. L. and Lockyer, N. P. (2013) Imaging of metabolites using secondary ion mass spectrometry. Metabolomics, 9(S1), pp. 102-109. (doi: 10.1007/s11306-012-0477-6)

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Abstract

This article provides an overview of the technique of secondary ion mass spectrometry imaging and highlights some current and future areas of application relevant to the field of metabolomics. The approach benefits from label-free analysis of molecular species up to ~1500 Da with minimal sample preparation. Offering the highest spatial resolution of current mass spectrometry imaging methodologies, the technique is well-suited to metabolite imaging in both biological tissue and cells, in both 2D and 3D.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Armitage, Dr Emily Grace
Authors: Armitage, E. G., Kotze, H. L., and Lockyer, N. P.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Metabolomics
Publisher:Springer
ISSN:1573-3882
ISSN (Online):1573-3890
Published Online:06 November 2012

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