The seroprevalence of hepatitis C virus infection among children and their mothers attending for dental care in Glasgow, Scotland, United Kingdom

O'Leary, M., Bagg, J. , Welbury, R., Hutchinson, S. J., Hague, R., Geary, I. and Roy, K. M. (2017) The seroprevalence of hepatitis C virus infection among children and their mothers attending for dental care in Glasgow, Scotland, United Kingdom. Journal of Infection and Public Health, 10(4), pp. 470-478. (doi:10.1016/j.jiph.2016.08.001) (PMID:27568000)

[img]
Preview
Text
121798.pdf - Accepted Version

392kB

Abstract

This paper describes a voluntary anonymous survey to investigate the seroprevalence of Hepatitis C (HCV) in children in Glasgow, UK attending a Dental Hospital and the proportion of HCV positive mothers who have a child who is HCV seropositive. The study was undertaken among children and accompanying parents and household contacts attending a general anaesthetic assessment clinic at Glasgow Dental Hospital and School. Children were asked to provide an oral fluid specimen for HCV testing. Accompanying adults were asked to provide demographic data on the child and information on familial risk factors for HCV infection using a standardised questionnaire. Birth mothers were also asked to provide an oral fluid specimen. Specimens and questionnaires were linked by a unique anonymous study number. Between June 2009 and December 2011, samples were collected from 2141 children and 1698 mothers. None of the samples from the children were HCV seropositive but 16 (0.9%, 95% CI 0.6% to 1.5%) of the specimens from mothers were HCV antibody positive. In summary, the prevalence of HCV seropositivity in the birth mothers of the children was similar to that estimated in the general population served by the hospital and showed no evidence of mother-to-child transmission of HCV.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Roy, Dr Kirsty and Geary, Mrs Isabella and Welbury, Professor Richard and Bagg, Professor Jeremy and Hague, Dr Rosie
Authors: O'Leary, M., Bagg, J., Welbury, R., Hutchinson, S. J., Hague, R., Geary, I., and Roy, K. M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Public Health
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Journal of Infection and Public Health
Publisher:Elsevier
ISSN:1876-0341
ISSN (Online):1876-035X
Published Online:24 August 2016
Copyright Holders:Copyright © 2016 King Saud Bin Abdulaziz University for Health Sciences
First Published:First published in Journal of Infection and Public Health 10(7):470-478
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

University Staff: Request a correction | Enlighten Editors: Update this record