Ménière's disease and underlying medical and mental conditions: towards factors contributing to the disease

Mohamed, S., Khan, I., Iliodromiti, S., Gaggini, M. and Kontorinis, G. (2016) Ménière's disease and underlying medical and mental conditions: towards factors contributing to the disease. ORL, 78(3), pp. 144-150. (doi: 10.1159/000444931) (PMID:27234349)

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Abstract

Purpose of the Study: To investigate the relation of Ménière's disease (MD) with medical comorbidity or mental conditions. Procedures: Demographic data, medical and mental comorbidities were retrospectively collected and compared from 3 groups of 30 patients each: a group with patients with definite MD, a second one with patients with vestibulopathies other than MD (non-Ménière's vertigo, NMV) and a third one with patients without any vestibular symptoms (control). The level of significance was set at 0.05. Results: The prevalence of mental conditions was 26.7, 23.3 and 6.7% for the MD, the NMV and the control group, respectively. Medical comorbidity was found in 80% of patients in the MD, 63% in the NMV and 20% in the control group. Arthritis was encountered in 8 patients with MD, 3 with NMV and none from the control group. The differences in prevalence of mental disease, comorbidities and arthritis between the MD and the control group were statistically significant (p = 0.02, p < 0.001 and p = 0.008, respectively). Conclusion: Psychological conditions play an important role in patients with MD. The significantly increased prevalence of arthritis in the MD group suggests an inflammatory/autoimmune background as a contributing factor to the disease.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Kontorinis, Mr Georgios and Khan, Mr Imran and Iliodromiti, Dr Stamatina
Authors: Mohamed, S., Khan, I., Iliodromiti, S., Gaggini, M., and Kontorinis, G.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:ORL
Publisher:S. Karger AG
ISSN:0301-1569
ISSN (Online):1423-0275
Published Online:28 May 2016

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