Simide, R., Angelier, F., Gaillard, S. and Stier, A. (2016) Age and heat stress as determinants of telomere length in a long-lived fish, the Siberian Sturgeon. Physiological and Biochemical Zoology, 89(5), pp. 441-447. (doi: 10.1086/687378) (PMID:27617363)
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Abstract
Telomeres shorten at each cell division due to the end-replication problem but also in response to oxidative stress. Consequently, telomeres shorten with age in many endotherms, and this shortening is accelerated under stressful environmental conditions. Data in ectotherm vertebrates remain scarce so far, so our goal was to review existing data for fish and to test the influence of age and stress on telomere length in a very long-lived fish, the Siberian sturgeon (Acipenser baerii). Our review of the literature revealed age-related telomere shortening in approximately half of the published studies. In the Siberian sturgeon, we found a significant telomere shortening with age, both at the intraindividual level using red blood cells (−12.5% in 16 mo) and at the interindividual level using cross-sectional samples of fin over an age range of 8 yr. We also found that heat stress (30°C) significantly reduced telomere length by 15.0% after only 1 mo of exposure. Our results highlight that both age and stressful environmental conditions might be important determinants of telomere length in fish.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Stier, Dr Antoine |
| Authors: | Simide, R., Angelier, F., Gaillard, S., and Stier, A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
| Journal Name: | Physiological and Biochemical Zoology |
| Publisher: | University of Chicago Press |
| ISSN: | 1522-2152 |
| ISSN (Online): | 1537-5293 |
| Published Online: | 17 June 2016 |
| Copyright Holders: | Copyright © 2016 University of Chicago Press |
| First Published: | First published in Physiological and Biochemical Zoology 89(5):441-447 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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