Predicting adverse events: detecting myocardial damage in intensive care unit (ICU) patients

Sleeman, D., Moss, L. , Sim, M. and Kinsella, J. (2011) Predicting adverse events: detecting myocardial damage in intensive care unit (ICU) patients. K-CAP 2011: The Sixth International Conference on Knowledge Capture, Banff, Alberta, Canada, 25-29 Jun 2011.

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Myocardial damage is known to occur relatively frequently, and although it is not often fatal it results in the patient staying in the ICU for significantly longer. Thus it is important for clinicians to detect these events. Confirmation of myocardial damage is by a biomarker (troponin), but these tests are only done at fixed timepoints. Consequently it is desirable for doctors, and support systems, to detect myocardial damage from the standard parameters collected for ICU patients. We have undertaken a study with several ICU consultants to determine the conditions which generally precede a myocardial-damaging event. In fact, these knowledge acquisition sessions produced a complex model which we have realized as 2 interacting modules. Subsequently, we compared this model’s predictions against the original datasets; the model when run against the test dataset resulted in a relatively high True Positive (TP) rate (75.8%). The implications of these analyses are discussed, as are a number of planned follow-up studies.

Item Type:Conference or Workshop Item
Glasgow Author(s) Enlighten ID:Sim, Malcolm and Kinsella, Professor John and Moss, Miss Laura
Authors: Sleeman, D., Moss, L., Sim, M., and Kinsella, J.
Subjects:R Medicine > R Medicine (General)
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Publisher:ACM Press
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