Ultrasound-Stimulated Mutual Interaction Forces between Optically Configured Micro-Bubble Pairs

Prentice, P. A. and Campbell, P. A. (2007) Ultrasound-Stimulated Mutual Interaction Forces between Optically Configured Micro-Bubble Pairs. In: 6th International Symposium on Therapeutic Ultrasound, Oxford, England, 30 Aug - 2 Sep 2007, pp. 212-218. ISBN 9780735404199 (doi:10.1063/1.2744275)

Prentice, P. A. and Campbell, P. A. (2007) Ultrasound-Stimulated Mutual Interaction Forces between Optically Configured Micro-Bubble Pairs. In: 6th International Symposium on Therapeutic Ultrasound, Oxford, England, 30 Aug - 2 Sep 2007, pp. 212-218. ISBN 9780735404199 (doi:10.1063/1.2744275)

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Abstract

The mutual interaction between two oscillating encapsulated microbubbles was investigated using a novel optical trapping arrangement. This approach facilitated the development of an arbitrary, stable, initial spatial configuration for a two‐bubble system. Critically, exercising optical control over such a binary bubble system meant that it could be isolated from the resident population of microbubbles during exposure to ultrasound. This ensured that any early stage dynamical evolution of the system was dominated by the mutual interaction of the two bubbles in view, rather than any extraneous influence arising from ‘crosstalk’ with the rest of the bubble population. We observed, using high speed microphotography at 4×105 frames per second, that the action of secondary radiation forces leads to mutual bubble attraction. Phenomena such as coalescence and ‘bounce’ were observed. Estimates of the microbubble [Sonovue™] compressibility could also be made, and tally well with published values obtained for other shelled contrast agents.

Item Type:Conference Proceedings
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Prentice, Dr Paul
Authors: Prentice, P. A., and Campbell, P. A.
College/School:College of Science and Engineering > School of Engineering > Systems Power and Energy
ISSN:0094-243X
ISBN:9780735404199
Published Online:21 May 2007

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