McQuilken, M. P., Gemmell, J., Hill, R. H. and Whipps, J. M. (2003) Production of macrosphelide A by the mycoparasite Coniothyrium minitans. FEMS Microbiology Letters, 219(1), pp. 27-31. (doi: 10.1016/S0378-1097(02)01180-1)
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Publisher's URL: http://dx.doi.org/10.1016/S0378-1097(02)01180-1
Abstract
<i>Coniothyrium minitans</i>, a mycoparasite of sclerotia of <i>Sclerotinia sclerotiorum</i> and <i>Sclerotium cepivorum</i>, produced four closely related metabolites inhibitory to fungal growth. The major metabolite, identified as macrosphelide A, had IG<sub>50</sub> values (the concentration of metabolite to inhibit growth by 50%) of 46.6 and 2.9 μg ml<sup>−1</sup> against <i>S. sclerotiorum</i> and <i>S. cepivorum</i>, respectively. This is the first report of both antifungal activity due to macrosphelide A as well as isolation of macrosphelide A from <i>C. minitans</i>.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Hill, Professor Robert |
| Authors: | McQuilken, M. P., Gemmell, J., Hill, R. H., and Whipps, J. M. |
| College/School: | College of Science and Engineering > School of Chemistry |
| Journal Name: | FEMS Microbiology Letters |
| Publisher: | Wiley |
| ISSN: | 0378-1097 |
| ISSN (Online): | 1574-6968 |
| Published Online: | 09 January 2006 |
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