Autophagy determines the path on the TRAIL to death

Sakamaki, J.-i. and Ryan, K. M. (2016) Autophagy determines the path on the TRAIL to death. Developmental Cell, 37(4), pp. 291-293. (doi:10.1016/j.devcel.2016.05.010) (PMID:27219055)

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Abstract

Macroautophagy facilitates degradation of cellular constituents and can positively or negatively affect cell death depending on the context. In this issue of Developmental Cell, Goodall and colleagues (2016) add to this complexity by showing that autophagy regulators can determine not only cell viability, but also the mechanism by which cells die.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ryan, Professor Kevin
Authors: Sakamaki, J.-i., and Ryan, K. M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Developmental Cell
Publisher:Elsevier
ISSN:1534-5807
ISSN (Online):1878-1551
Published Online:23 May 2016

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