Risk assessment of renal cortical scarring with urinary tract infection by clinical features and ultrasonography

Christian, M.T., McColl, J.H. , MacKenzie, J.R. and Beattie, T.J. (2000) Risk assessment of renal cortical scarring with urinary tract infection by clinical features and ultrasonography. Archives of Disease in Childhood, 82(5), pp. 376-380. (doi: 10.1136/adc.82.5.376) (PMID:10799427) (PMCID:PMC1718320)

Full text not currently available from Enlighten.

Abstract

AIMS: To address some of the issues in the ongoing debate over the optimal diagnostic imaging following childhood urinary tract infection (UTI), by determining the risk of missing renal cortical scarring which would be detected on a technetium-99m dimercaptosuccinic acid (DMSA) gold standard if ultrasound alone were used, factoring for clinical features (upper or lower tract), UTI recurrence, and age group (infants, preschool, or school age). METHODS: Details of UTI clinical features and recurrence were recorded for 990 children with a proven UTI, and their DMSA and ultrasound results were compared for each kidney. RESULTS: The risks of missing DMSA scarring varied between 0.4% (school age children with solitary lower tract UTI) and 11.1% (infants with recurrent upper tract UTI). CONCLUSIONS: UTI clinical features are important in assessing the need for DMSA imaging. Current UK imaging guidelines are endorsed, although preschool children with solitary lower tract UTI remain a controversial group and more attention needs to focused on children with recurrent UTI.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McColl, Professor John
Authors: Christian, M.T., McColl, J.H., MacKenzie, J.R., and Beattie, T.J.
College/School:College of Science and Engineering > School of Mathematics and Statistics > Statistics
Journal Name:Archives of Disease in Childhood
Publisher:BMJ Group
ISSN:0003-9888
ISSN (Online):1468-2044

University Staff: Request a correction | Enlighten Editors: Update this record