Sans Sangorrin, V. and Cronin, L. (2016) Towards dial-a-molecule by integrating continuous flow, analytics and self-optimisation. Chemical Society Reviews, 45(8), pp. 2032-2043. (doi: 10.1039/C5CS00793C) (PMID:26815081) (PMCID:PMC6057606)
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Abstract
The employment of continuous-flow platforms for synthetic chemistry is becoming increasingly popular in research and industrial environments. Integrating analytics in-line enables obtaining a large amount of information in real-time about the reaction progress, catalytic activity and stability, etc. Furthermore, it is possible to influence the reaction progress and selectivity via manual or automated feedback optimisation, thus constituting a dial-a-molecule approach employing digital synthesis. This contribution gives an overview of the most significant contributions in the field to date.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Cronin, Professor Lee and Sans Sangorrin, Dr Victor |
Authors: | Sans Sangorrin, V., and Cronin, L. |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Chemical Society Reviews |
Publisher: | Royal Society of Chemistry |
ISSN: | 0306-0012 |
ISSN (Online): | 1460-4744 |
Published Online: | 27 January 2016 |
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