Self-generated chemotactic gradients—cells steering themselves

Tweedy, L., Susanto, O. and Insall, R. H. (2016) Self-generated chemotactic gradients—cells steering themselves. Current Opinion in Cell Biology, 42, pp. 46-51. (doi: 10.1016/ (PMID:27105308)

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Chemotaxis is a fundamentally important part of biology, but we know very little about how gradients of chemoattractant are formed. One answer is self-generated gradients, in which the moving cells break down the attractant to provide their own gradient as they migrate. Here we discuss where self-generated gradients are known, how they can be recognized, and where they are likely to be found in the future.

Item Type:Articles
Additional Information:LT, OS and RI are funded by a core institute grant from Cancer Research UK to RI.
Glasgow Author(s) Enlighten ID:Susanto, Dr Olivia and Insall, Professor Robert
Authors: Tweedy, L., Susanto, O., and Insall, R. H.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Current Opinion in Cell Biology
ISSN (Online):1879-0410
Published Online:19 April 2016
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