Mesenchymal stem cell fate: applying biomaterials for control of stem cell behaviour

Anderson, H. J., Dalby, M. J. , Sahoo, J. and Uljin, R. (2016) Mesenchymal stem cell fate: applying biomaterials for control of stem cell behaviour. Frontiers in Bioengineering and Biotechnology, 4, 38. (doi:10.3389/fbioe.2016.00038) (PMID:27242999) (PMCID:PMC4865671)

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Publisher's URL: http://journal.frontiersin.org/article/10.3389/fbioe.2016.00038/abstract

Abstract

The materials pipeline for biomaterials and tissue engineering applications is under continuous development. Specifically, there is great interest in the use of designed materials in the stem cell arena as materials can be used to manipulate the cells providing control of behaviour. This is important as the ability to ‘engineer’ complexity and subsequent in vitro growth of tissues and organs is a key objective for tissue engineers. This review will describe the nature of the materials strategies, both static and dynamic, and their influence specifically on mesenchymal stem cell fate.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:ANDERSON, Hilary and Dalby, Professor Matthew
Authors: Anderson, H. J., Dalby, M. J., Sahoo, J., and Uljin, R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
Journal Name:Frontiers in Bioengineering and Biotechnology
Publisher:Frontiers
ISSN:2296-4185
Published Online:18 April 2016
Copyright Holders:Copyright © 2016 Anderson, Dalby, Sahoo and Uljin
First Published:First published in Frontiers in Bioengineering and Biotechnology 4:38
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
470563DTC in cell and proteomic technologies (continuation)Jonathan CooperEngineering & Physical Sciences Research Council (EPSRC)EP/F500424/1ENG - BIOMEDICAL ENGINEERING
608751Dynamic surfaces to mimic mesenchymal stem cell niche functionsMatthew DalbyBiotechnology and Biological Sciences Research Council (BBSRC)BB/K006908/1RI MOLECULAR CELL & SYSTEMS BIOLOGY