Lei, K.-M., Heidari, H. , Mak, P.-I., Law, M.-K., Maloberti, F. and Martins, R. P. (2016) A Handheld 50pM-Sensitivity Micro-NMR CMOS Platform with B-Field Stabilization for Multi-Type Biological/Chemical Assays. In: IEEE international Solid-State Circuits Conference (ISSCC), San Fransisco, CA, 31 Jan - 4 Feb 2016, pp. 474-476.
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Abstract
Point-of-use (PoU) biological/chemical assays are aimed to transform bulky laboratory instruments into easy-to-use lab-on-a-chip platforms, bringing down the cost, size, and sample-use by orders of magnitude [1,2]. Micro-Nuclear Magnetic Resonance (NMR) is a trail-blazing tool for target pinpointing, by utilizing functionalized magnetic nanoparticles (MNPs) as the probe [3]. Screening by micro-NMR is repeatable, versatile and low-cost as it is label- and washing free for the samples, and immobilization-free for the electrodes. Herein, a high-sensitivity micro-NMR CMOS platform with magnetic (B)-field stabilization and thermal management is reported (Fig. 28.1.1). This handheld tool unifies multi-type assays (target detection, protein state analysis, and solvent-polymer dynamics), and is suitable for healthcare, food industry, and colloidal applications.
| Item Type: | Conference Proceedings |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Heidari, Professor Hadi |
| Authors: | Lei, K.-M., Heidari, H., Mak, P.-I., Law, M.-K., Maloberti, F., and Martins, R. P. |
| College/School: | College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering |
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