Predictors of quality of life in head and neck cancer survivors up to 5 years after end of treatment: a cross-sectional survey

Wells, M., Swartzman, S., Lang, H., Cunningham, M., Taylor, L., Thomson, J., Philp, J. and Mccowan, C. (2016) Predictors of quality of life in head and neck cancer survivors up to 5 years after end of treatment: a cross-sectional survey. Supportive Care in Cancer, 24(6), pp. 2463-2472. (doi:10.1007/s00520-015-3045-6) (PMID:26660345)

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Abstract

PURPOSE This study aimed to assess quality of life (QoL) in head and neck cancer (HNC) survivors and determine factors predictive of poor QoL in the first 5 years after the end of treatment. METHODS A cross-sectional survey, including the Quality of Life in Adult Cancer Survivors (QLACS) measure, was sent to HNC survivors in three Scottish health regions, with responses linked to routinely collected clinical data. Independent sample t tests, ANOVAs, Pearson correlations and multiple hierarchical regressions were used to explore associations between and to determine the contribution made by demographic, lifestyle and clinical factors to predicting 'generic' and 'cancer-specific' quality of life. RESULTS Two hundred eighty patients (65 %) returned questionnaires. After adjustment, multivariate analysis showed that younger age, lower socio-economic status, unemployment and self-reported comorbidity independently contributed to poorer generic and cancer-specific quality of life. In addition to these factors, having had a feeding tube or a diagnosis of oral cavity cancer were independently predictive of poorer cancer-specific quality of life. CONCLUSIONS Socio-economic factors and comorbidity are important predictors of QoL in HNC survivors. These factors and the detrimental long-term effects of feeding tubes need further attention in research and practice.

Item Type:Articles (Other)
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Mccowan, Professor Colin
Authors: Wells, M., Swartzman, S., Lang, H., Cunningham, M., Taylor, L., Thomson, J., Philp, J., and Mccowan, C.
Subjects:R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Robertson Centre
Journal Name:Supportive Care in Cancer
Publisher:Springer Berlin Heidelberg
ISSN:0941-4355
ISSN (Online):1433-7339
Published Online:11 December 2015
Copyright Holders:Copyright © 2016 Springer Berlin Heidelberg
First Published:First published in Supportive Care in Cancer 24(6):2463-2472
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher.

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