Phytochemical compounds involved in the anti-inflammatory effect of propolis extract

Borrelli, F., Maffia, P. , Pinto, L., Ianaro, A., Russo, A., Capasso, F. and Ialenti, A. (2002) Phytochemical compounds involved in the anti-inflammatory effect of propolis extract. Fitoterapia, 73(Supl 1), S53-S63. (doi:10.1016/S0367-326X(02)00191-0) (PMID:12495710)

Full text not currently available from Enlighten.

Abstract

Two ethanolic propolis extracts (EPE) with and without the caffeic acid phenethyl ester (CAPE), CAPE and galangin (major components of propolis) were investigated for anti-inflammatory activity in rats using carrageenin foot oedema, carrageenin pleurisy and adjuvant arthritis. In our experiments, EPE with CAPE and CAPE alone significantly inhibited carrageenin oedema, carrageenin pleurisy and adjuvant arthritis. In contrast EPE without CAPE and galangin did not exhibit anti-inflammatory effects in acute and chronic inflammation. These results suggest that the anti-inflammatory activity of propolis is due to CAPE.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Maffia, Dr Pasquale
Authors: Borrelli, F., Maffia, P., Pinto, L., Ianaro, A., Russo, A., Capasso, F., and Ialenti, A.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Fitoterapia
Publisher:Elsevier Science Inc.
ISSN:0367-326X

University Staff: Request a correction | Enlighten Editors: Update this record