Progress in inflammatory neuropathy :the legacy of Dr Jack Griffin

Feldman, E. L., Hughes, R. A.C. and Willison, H. (2015) Progress in inflammatory neuropathy :the legacy of Dr Jack Griffin. Nature Reviews Neurology, 11(11), pp. 646-650. (doi: 10.1038/nrneurol.2015.192) (PMID:26458287)

Full text not currently available from Enlighten.


The past quarter of a century has brought incredible advances in our understanding of inflammatory neuropathies, and the insights into Guillain–Barré syndrome (GBS) began in the 1990s with the seminal work of Dr Jack Griffin and his colleagues. In this essay, we provide a tribute to Jack, and review the recent progress in a field that he termed his personal favourite. In particular, we discuss the new developments in our understanding and diagnosis of inflammatory neuropathies, the recent emergence of the node of Ranvier and the paranode as sites of intensive investigation, and the mechanistic evidence that is providing a platform for therapeutic development studies.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Willison, Professor Hugh
Authors: Feldman, E. L., Hughes, R. A.C., and Willison, H.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:Nature Reviews Neurology
Publisher:Nature Publishing Group
ISSN (Online):1759-4766

University Staff: Request a correction | Enlighten Editors: Update this record