Non-exercise equations to estimate fitness in white European and South Asian men

O'Donovan, G. et al. (2016) Non-exercise equations to estimate fitness in white European and South Asian men. Medicine and Science in Sports and Exercise, 48(5), pp. 854-859. (doi: 10.1249/MSS.0000000000000836) (PMID:26694847)

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Cardiorespiratory fitness is a strong, independent predictor of health, whether it is measured in an exercise test or estimated in an equation. The purpose of this study was to develop and validate equations to estimate fitness in middle-aged white European and South Asian men.Multiple linear regression models (n=168, including 83 white European and 85 South Asian men) were created using variables that are thought to be important in predicting fitness (VO2 max, mL⋅kg⋅min): age (years); BMI (kg·m); resting heart rate (beats⋅min); smoking status (0=never smoked, 1=ex or current smoker); physical activity expressed as quintiles (0=quintile 1, 1=quintile 2, 2=quintile 3, 3=quintile 4, 4=quintile 5), categories of moderate- to vigorous-intensity physical activity (0=<75 min⋅wk, 1=75-150 min⋅wk, 2=>150-225 min⋅wk, 3=>225-300 min⋅wk, 4=>300 min⋅wk), or minutes of moderate- to vigorous-intensity physical activity (min⋅wk); and, ethnicity (0=South Asian, 1=white). The leave-one-out-cross-validation procedure was used to assess the generalizability and the bootstrap and jackknife resampling techniques were used to estimate the variance and bias of the models.Around 70% of the variance in fitness was explained in models with an ethnicity variable, such as: VO2 max = 77.409 - (age*0.374) - (BMI*0.906) - (ex or current smoker*1.976) + (physical activity quintile coefficient) - (resting heart rate*0.066) + (white ethnicity*8.032), where physical activity quintile 1 is 1, 2 is 1.127, 3 is 1.869, 4 is 3.793, and 5 is 3.029. Only around 50% of the variance was explained in models without an ethnicity variable. All models with an ethnicity variable were generalizable and had low variance and bias.These data demonstrate the importance of incorporating ethnicity in non-exercise equations to estimate cardiorespiratory fitness in multi-ethnic populations.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Gill, Professor Jason and Ghouri, Dr Nazim and Sattar, Professor Naveed
Authors: O'Donovan, G., Bakrania, K., Ghouri, N., Yates, T., Gray, L. J., Hamer, M., Stamatakis, E., Khunti, K., Davies, M., Sattar, N., and Gill, J. M.R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Medicine and Science in Sports and Exercise
Publisher:American College of Sports Medicine
ISSN (Online):1530-0315
Copyright Holders:Copyright © 2015 American College of Sports Medicine
First Published:First published in Medicine and Science in Sports and Exercise 48(5): 854-859
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher.

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