Fluid-structure interaction model of human mitral valve within left ventricle

Gao, H. , Qi, N., Ma, X., Griffith, B. E., Berry, C. and Luo, X. (2015) Fluid-structure interaction model of human mitral valve within left ventricle. In: Functional Imaging and Modeling of the Heart. Series: Lecture Notes in Computer Science, 9126 (9126). Springer International Publishing, pp. 330-337. ISBN 9783319203089 (doi:10.1007/978-3-319-20309-6_38)

113081.pdf - Accepted Version



We present an integrated model of mitral valve coupled with the left ventricle. The model is derived from clinical images and takes into account of the important valvular features, left ventricle contraction, nonlinear soft tissue mechanics, fluid structure interaction, and the MV-LV interaction. This model is compared with a corresponding mitral-tube model, and differences in the results are discussed. Although the model is a step closer towards simulating physiological realistic situation, further work is required to ensure that the highly complex valvular-ventricular interaction, and the fluid-structure interaction, can be reliably represented.

Item Type:Book Sections
Additional Information:8th International Conference, FIMH 2015, Maastricht, The Netherlands, June 25-27, 2015. Proceedings
Glasgow Author(s) Enlighten ID:Berry, Professor Colin and Gao, Dr Hao
Authors: Gao, H., Qi, N., Ma, X., Griffith, B. E., Berry, C., and Luo, X.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Journal Name:Fluid-Structure Interaction Model of Human Mitral Valve within Left Ventricle
Publisher:Springer International Publishing
Copyright Holders:Copyright © 2015 Springer International Publishing
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
662681"First steps towards modelling myocardial infarction (a computed MI Physiome): A case-control study of novel biomechanical parameters in acute MI survivors with left ventricular dysfunction."Colin BerryBritish Heart Foundation (BHF)PG/14/64/31043RI CARDIOVASCULAR & MEDICAL SCIENCES