Presumed brain infarctions in two dogs with systemic leishmaniasis

Jose-Lopez, R. , de la Fuente, C. and Añor, S. (2012) Presumed brain infarctions in two dogs with systemic leishmaniasis. Journal of Small Animal Practice, 53(9), pp. 554-7. (doi: 10.1111/j.1748-5827.2012.01259.x) (PMID:22882167)

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Abstract

Clinical signs and magnetic resonance imaging findings of multiple brain infarcts in two dogs infected with Leishmania spp. are reported. Clinical signs of intracranial dysfunction were peracute and there was no further deterioration. Magnetic resonance images of the brain were consistent with multifocal, non-haemorrhagic, ischaemic lesions. Routine serum biochemistry revealed hyperproteinaemia and hyperglobulinaemia. Serum antibody titres were highly positive for Leishmania infantum and Leishmania amastigotes were seen within bone marrow macrophages in both cases. Canine leishmaniasis can cause cerebrovascular alterations, such as vasculitis, that might predispose dogs to brain infarcts.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Jose-Lopez, Mr Roberto
Authors: Jose-Lopez, R., de la Fuente, C., and Añor, S.
College/School:College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Journal Name:Journal of Small Animal Practice
Publisher:Wiley-Blackwell Publishing Ltd.
ISSN:1748-5827
ISSN (Online):1748-5827

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