A survey of attitudes towards the clinical application of systemic inflammation based prognostic scores in cancer

Watt, D., Roxburgh, C. , White, M., Chan, J., Horgan, P. and McMillan, D. (2015) A survey of attitudes towards the clinical application of systemic inflammation based prognostic scores in cancer. Mediators of Inflammation, 2015, 842070. (doi:10.1155/2015/842070) (PMID:26504363) (PMCID:PMC4609481)

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Abstract

Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The aim of the present survey was to examine the range of opinions internationally on the routine use of these scoring systems. Methods. An online survey was distributed to a target group consisting of individuals worldwide who have reported an interest in systemic inflammation in patients with cancer. Results. Of those invited by the survey (), 65% routinely measured the SIR, mainly for research and prognostication purposes and clinically for allocation of adjuvant therapy or palliative chemotherapy. 40% reported that they currently used the Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS) and 81% reported that a measure of systemic inflammation should be incorporated into clinical guidelines, such as the definition of cachexia. Conclusions. The majority of respondents routinely measured the SIR in patients with cancer, mainly using the GPS/mGPS for research and prognostication purposes. The majority reported that a measure of the SIR should be adopted into clinical guidelines.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Horgan, Professor Paul and Roxburgh, Dr Campbell and McMillan, Professor Donald and White, Dr Mark and Watt, Dr David
Authors: Watt, D., Roxburgh, C., White, M., Chan, J., Horgan, P., and McMillan, D.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Mediators of Inflammation
Publisher:Hindawi Publishing Corporation
ISSN:0962-9351
ISSN (Online):1466-1861
Copyright Holders:Copyright © 2015 David G. Watt et al.
First Published:First published in Mediators of Inflammation 2015:842070
Publisher Policy:Reproduced under a Creative Commons License

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