Modelling Afferent Nerve Responses to Bladder Filling

Argungu, M. et al. (2015) Modelling Afferent Nerve Responses to Bladder Filling. UK MMSG NC3R’s & POEMS Study Group Meeting, Cambridge, UK, 8-12 Sept 2014.

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Publisher's URL: http://www.maths-in-medicine.org/uk/2014/bladder-filling/

Abstract

A sensation of fullness in the bladder is a regular experience, yet the mechanisms that act to generate this sensation remain poorly understood. This is an important issue because of the clinical problems that can result when this system does not function properly. The aim of the study group activity was to develop mathematical models that describe the mechanics of bladder filling, and how stretch modulates the firing rate of afferent nerves. Several models were developed, which were qualitatively consistent with experimental data obtained from a mouse model.

Item Type:Conference or Workshop Item
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Simitev, Dr Radostin
Authors: Argungu, M., Bayram, S., Brook, B., Chakrabarti, B., Clayton, R. H., Daly, D. M., Dyson, R. J., Holloway, C., Manhas, V., Naire, S., Shearer, T., and Simitev, R. D.
College/School:College of Science and Engineering > School of Mathematics and Statistics > Mathematics
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