To replay, perchance to consolidate

Genzel, L. and Robertson, E. (2015) To replay, perchance to consolidate. PLoS Biology, 13(10), e1002285. (doi: 10.1371/journal.pbio.1002285) (PMID:26496145) (PMCID:PMC4619867)

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After a memory is formed, it continues to be processed by the brain. These “off-line” processes consolidate the memory, leading to its enhancement and to changes in memory circuits. Potentially, these memory changes are driven by off-line replay of the pattern of neuronal activity present when the memory was being formed. A new study by Dhaksin Ramanathan and colleagues, published in PLOS Biology, demonstrates that replay occurs predominately after the acquisition of a new motor skill and that it is related to changes in memory performance and to the subsequent changes in memory circuits. Together, these observations reveal the importance of neuronal replay in the consolidation of novel motor skills.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Robertson, Professor Edwin
Authors: Genzel, L., and Robertson, E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
Journal Name:PLoS Biology
Publisher:Public Library of Science
ISSN (Online):1544-9173
Copyright Holders:Copyright © 2015 Genzel, Robertson
First Published:First published in PLoS Biology 13(10):e1002285
Publisher Policy:Reproduced under a Creative Commons License

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