Oestrogen replacement in postmenopausal women

Sassarini, J. and Lumsden, M. A. (2015) Oestrogen replacement in postmenopausal women. Age and Ageing, 44(4), pp. 551-558. (doi: 10.1093/ageing/afv069) (PMID:26070875)

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Menopausal symptoms can disrupt a woman's personal and social life. Vasomotor symptoms (hot flushes and night sweats) are the most common symptoms and can be treated very effectively with oestrogen-based hormone therapy. The decision to use oestrogen (often simply termed hormone therapy or hormone replacement therapy or HT) therapy involves balancing the potential benefits against the potential risks. Most agree that short-term oestrogen therapy, using the lowest effective dose, is a reasonable option for recently menopausal women with moderate-to-severe symptoms who are in good cardiovascular health (Martin and Manson. 2008. J. Clin. Endocrinol. Metab. 93, 4567–75). Whilst effective and safe in most instances, HT is not suitable for all women or for all menopause-related symptoms when alternatives are available. The role of HRT in chronic disease prevention is also discussed.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Sassarini, Dr Jenifer and Lumsden, Professor Mary
Authors: Sassarini, J., and Lumsden, M. A.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Age and Ageing
Publisher:Oxford University Press
ISSN (Online):1468-2834

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