Cell response to nano-islands produced by polymer demixing: a brief review

Dalby, M.J. , Pasqui, D. and Affrossman, S. (2004) Cell response to nano-islands produced by polymer demixing: a brief review. IEE Proceedings: Nanobiotechnology, 151(2), pp. 53-61. (doi:10.1049/ip-nbt:20040534)

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Abstract

This review looks at the present literature available regarding cell response to nano-islands produced by nanotopography. Polymer demixing is a chemical method of fabricating large areas of nanotopography quickly and cheaply, making it ideal for cell testing and thus allowing it to be one of the first well-researched methods in cell engineering. The review shows that cells respond strongly to the islands (cell types observed include endothelial cells, fibroblasts, osteoblasts, leucocytes and platelets). Such changes include differences in adhesion, growth, gene expression and morphology.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Dalby, Professor Matthew
Authors: Dalby, M.J., Pasqui, D., and Affrossman, S.
Subjects:T Technology > T Technology (General)
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
Journal Name:IEE Proceedings: Nanobiotechnology
Journal Abbr.:IEE proc., Nanobiotechnol.
ISSN:1478-1581
ISSN (Online):1740-9748
Published Online:01 June 2004

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