Heart rate and use of -blockers in Mexican stable outpatients with coronary artery disease

Alcocer-Gamba, M. A., Martínez-Sánchez, C., Verdejo-Paris, J., Ferrari, R., Fox, K., Greenlaw, N. and Steg Philippe, G. (2015) Heart rate and use of -blockers in Mexican stable outpatients with coronary artery disease. Archivos de Cardiología de México, pp. 270-277. (doi:10.1016/j.acmx.2015.01.004) (PMID:25921309)

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Abstract

Objective To evaluate the use of β-blockers and to monitor heart rate in Mexican patients with coronary artery disease. Methods CLARIFY is an outpatients registry with stable CAD. A total of 33,283 patients from 45 countries were enrolled between November 2009 and July 2010 from which 1342 were Mexican patients. Results The mean HR pulse was 70bpm (beats per minute). Patients in Mexico were compared with the remaining global CLARIFY population. Patients in Mexico had a higher incidence of acute myocardial infarction and percutaneous coronary intervention, and lower incidence of revascularization surgery compared with the remaining CLARIFY population. More often, Mexican patients presented with diabetes, but less often hypertension and stroke. These patients were split into three mutually exclusive groups of HR ≤60 (N=263), HR 61–69 (N=356) and HR ≥70 (N=722). Patients with elevated HR had a higher incidence of diabetes and higher diastolic blood pressure on average than those with controlled HR. Regarding the use of β-blockers, they were used in 63.3% of patients, 2.7% showed intolerance or contraindication to treatment to monitor heart rate, and ivabradine was used in 2.3%. Out of approximately 849 patients receiving treatment of β-blockers, 52.1% had ≥70bpm HR. Conclusions In a large proportion of Mexican patients with stable coronary disease the HR remain elevated, >70bpm, even with the use of β-blockers; this requires further attention.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Greenlaw, Miss Nicola
Authors: Alcocer-Gamba, M. A., Martínez-Sánchez, C., Verdejo-Paris, J., Ferrari, R., Fox, K., Greenlaw, N., and Steg Philippe, G.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Robertson Centre
Journal Name:Archivos de Cardiología de México
Publisher:Masson Doyma México S.A
ISSN:1405-9940

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