The visual language of synteny

Hunt, E., Hanlon, N., Leader, D.P., Bryce, H. and Dominiczak, A.F. (2004) The visual language of synteny. OMICS: A Journal of Integrative Biology, 8(4), pp. 289-305. (doi: 10.1089/omi.2004.8.289.)

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The study of polygenic disorders such as cardiovascular and metabolic diseases requires access to vast amounts of experimental and in silico data. Where animal models of disease are being used, visualization of syntenic genome regions is one of the most important tools supporting data analysis. We define what is required to visualize synteny in terms of the data being displayed, the screen layout, and user interaction. We then describe a prototype visualization tool, SyntenyVista, which provides integrated access to quantitative trait loci, microarray, and gene datasets. We believe that SyntenyVista is a significant step towards an improved representation of comparative genomics data.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Dominiczak, Professor Anna and Leader, Dr David
Authors: Hunt, E., Hanlon, N., Leader, D.P., Bryce, H., and Dominiczak, A.F.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
Journal Name:OMICS: A Journal of Integrative Biology

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