Linear microrheology with optical tweezers of living cells 'is not an option'!

Tassieri, M. (2015) Linear microrheology with optical tweezers of living cells 'is not an option'! Soft Matter, 11, pp. 5792-5798. (doi:10.1039/C5SM01133G) (PMID:26100967)

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Optical tweezers have been successfully adopted as exceptionally sensitive transducers for microrheology studies of complex fluids. Despite the general trend, in this article I explain why a similar approach should not be adopted for microrheology studies of living cells. This conclusion is reached on the basis of statistical mechanics principles that indicate the unsuitability of optical tweezers for such purpose.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Tassieri, Dr Manlio
Authors: Tassieri, M.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Soft Matter
Publisher:Royal Society of Chemistry
ISSN (Online):1744-6848
Copyright Holders:Copyright © 2015 The Royal Society of Chemistry
First Published:First published in Soft Matter 11:5792-5798
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
534472Rheology at the Microscale: New Tools for Bio-analysisManlio TassieriEngineering & Physical Sciences Research Council (EPSRC)10216/101ENG - BIOMEDICAL ENGINEERING