Investigation of the optimal collagen fibre orientation in human iliac arteries

Qi, N., Gao, H. , Ogden, R. W. , Hill, N. A. , Holzapfel, G. A., Han, H. and Luo, X. (2015) Investigation of the optimal collagen fibre orientation in human iliac arteries. Journal of the Mechanical Behavior of Biomedical Materials, 52, pp. 108-119. (doi:10.1016/j.jmbbm.2015.06.011) (PMID:26195342)

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Abstract

The distribution of collagen fibres plays a significant role in the mechanical behaviour of artery walls. Experimental data show that in most artery wall layers there are two (or more) in-plane symmetrically disposed families of fibres. However, a recent investigation revealed that some artery wall layers have only one preferred fibre direction, notably in the medial layer of human common iliac arteries. This paper aims to provide a possible explanation for this intriguing phenomenon. An invariant-based constitutive model is utilized to characterize the mechanical behaviour of tissues. We then use three different hypotheses to determine the ‘optimal fibre angle’ in an iliac artery model. All three hypotheses lead to the same result that the optimal fibre angle in the medial layer of the iliac artery is close to the circumferential direction. The axial pre-stretch, in particular, is found to play an essential role in determining the optimal fibre angle.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Luo, Professor Xiaoyu and Hill, Professor Nicholas and Ogden, Professor Raymond and Gao, Dr Hao and Holzapfel, Professor Gerhard
Authors: Qi, N., Gao, H., Ogden, R. W., Hill, N. A., Holzapfel, G. A., Han, H., and Luo, X.
College/School:College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Journal Name:Journal of the Mechanical Behavior of Biomedical Materials
Publisher:Elsevier
ISSN:1751-6161
ISSN (Online):1878-0180
Copyright Holders:Copyright © 2015 The Authors
First Published:First published in Journal of the Mechanical Behavior of Biomedical Materials
Publisher Policy:Reproduced under a Creative Commons License

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