Acute disseminated encephalomyelitis: current knowledge and open questions

Steiner, I. and Kennedy, P. G. E. (2015) Acute disseminated encephalomyelitis: current knowledge and open questions. Journal of Neurovirology, 21(5), pp. 473-479. (doi: 10.1007/s13365-015-0353-z) (PMID:26037112)

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Abstract

Acute disseminated encephalomyelitis (ADEM) is usually an acute, multi-focal, and monophasic immune-mediated disease of the central nervous system. The disorder is mainly a condition of the pediatric age group, but neurologists are also involved in the management of adult patients. The lack of defined diagnostic criteria for ADEM underlies the limited understanding of its epidemiology, etiology, pathogenesis, course, prognosis, therapy, as well as the association with, and distinction from, multiple sclerosis. The present review summarizes current knowledge and outlines unanswered questions the answers to which should be eventually provided through a synergistic combination of clinical and basic research.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Kennedy, Professor Peter
Authors: Steiner, I., and Kennedy, P. G. E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Neurovirology
Journal Abbr.:J. Neurovirol.
Publisher:Springer US
ISSN:1355-0284
ISSN (Online):1538-2443

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