Blunted cardiomyocyte remodeling response in exercise-resistant rats

Wisløff, U., Bye, A., Stølen, T., Kemi, O. J. , Pollott, G. E., Pande, M., McEachin, R. C., Britton, S. L. and Koch, L. G. (2015) Blunted cardiomyocyte remodeling response in exercise-resistant rats. Journal of the American College of Cardiology, 65(13), pp. 1378-1380. (doi: 10.1016/j.jacc.2015.01.041) (PMID:25835453)

Abstract

Increasing a subject’s aerobic exercise capacity with training decreases cardiovascular morbidity and mortality. Of major concern is the key observation that up to 20% of subjects demonstrate little or no change in maximal oxygen consumption (VO2max) with exercise training (1) and can be considered exercise resistant. Our goal with the current research was to test the hypothesis that variation in training response is associated with cardiomyocyte functional response to training.

• Item Type: Articles (Letter)
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Kemi, Dr Ole
• Authors: Wisløff, U., Bye, A., Stølen, T., Kemi, O. J., Pollott, G. E., Pande, M., McEachin, R. C., Britton, S. L., and Koch, L. G.
• College/School: College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
• Journal Name: Journal of the American College of Cardiology
• Publisher: Elsevier Inc.
• ISSN: 0735-1097
• Copyright Holders: Copyright © 2015 American College of Cardiology Foundation
• First Published: First published in Journal of the American College of Cardiology 65(13):1378-1380
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher.