Long term treatment with rifampicin for pruritis has implications for warfarin use

Bound, B.L., Johnstone, L. and McKay, G.A. (2009) Long term treatment with rifampicin for pruritis has implications for warfarin use. Scottish Medical Journal, 54(1), p. 58. (doi:10.1258/rsmsmj.54.1.58g)

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Abstract

Warfarin is an established treatment method for anticoagulating patients following diagnosis of deep vein thrombosis (DVT). We present a patient who was on rifampicin treatment for pruritis, secondary to primary biliary cirrhosis (PBC), who was diagnosed with a DVT post operatively. A therapeutic INR was not obtained following fourteen days of warfarin treatment due to a drug interaction with rifampicin. We review the use of rifampicin for pruritis in PBC and the mechanism of interaction between warfarin and rifampicin.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McKay, Dr Gerard
Authors: Bound, B.L., Johnstone, L., and McKay, G.A.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Scottish Medical Journal
Publisher:SAGE Publications
ISSN:0036-9330
ISSN (Online):2045-6441

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