ISCOMS — a novel strategy for mucosal immunization?

Mowat, A. M. and Donachie, A. M. (1991) ISCOMS — a novel strategy for mucosal immunization? Immunology Today, 12(11), pp. 383-385. (doi: 10.1016/0167-5699(91)90133-E) (PMID:1786069)

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Orally-active vaccines containing purified or recombinant antigens are highly desirable, particularly in immunization against diseases of mucosal surfaces, but their development to date has been limited and fitful, hampered by a range of difficulties. Here, Allan Mowat and Anne Donachie suggest that lipophilic immune-stimulating complexes (ISCOMS) may provide an oral immunization vector for the induction of a wide range of immune responses to protein antigens.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Mowat, Professor Allan and Donachie, Ms Anne Marie
Authors: Mowat, A. M., and Donachie, A. M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Immunology Today

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