Metabolic syndrome sinkholes: what to do when Occam's razor gets blunted

Feldman, R. D., Anderson, T. J. and Touyz, R. M. (2015) Metabolic syndrome sinkholes: what to do when Occam's razor gets blunted. Canadian Journal of Cardiology, 31(5), pp. 601-604. (doi: 10.1016/j.cjca.2014.12.035) (PMID:25936488)

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Abstract

The real promise of the metabolic syndrome concept was the opportunity to elucidate a singular common mechanism for its component abnormalities and consequently a singular therapy. That promise has not produced. This relates to the following considerations: (1) metabolic syndrome remains a syndrome not a disease, (2) its diagnosis offers little more than what can be determined by measuring waist circumference, (3) risk assessment is not improved by the diagnosis of metabolic syndrome, (4) the diagnosis of metabolic syndrome does not impact the treatment of each component of the syndrome, and (5) there is no effective therapy for metabolic syndrome in its entirety.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Touyz, Professor Rhian
Authors: Feldman, R. D., Anderson, T. J., and Touyz, R. M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Canadian Journal of Cardiology
Publisher:Elsevier
ISSN:0828-282X
ISSN (Online):1916-7075

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