Uptake and localization mechanisms of fluorescent and colored lipid probes: part 3. protocols for predicting intracellular localization of lipid probes using QSAR models

Horobin, R.W. , Stockert, J.C. and Rashid-Doubell, F. (2015) Uptake and localization mechanisms of fluorescent and colored lipid probes: part 3. protocols for predicting intracellular localization of lipid probes using QSAR models. Biotechnic and Histochemistry, 90(4), pp. 255-263. (doi: 10.3109/10520295.2015.1006680) (PMID:25801295)

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Abstract

We provide detailed protocols for applying the QSAR decision-rule models described in Part 2 of this paper. These procedures permit prediction of the intracellular localization of fluorescent probes or of any small molecular xenobiotic whether fluorescent or not. Also included is a set of notes that give practical advice on various possible problems and limitations of the methods, together with a flow chart that provides a graphical algorithmic summary of the QSAR models.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Horobin, Dr Richard
Authors: Horobin, R.W., Stockert, J.C., and Rashid-Doubell, F.
College/School:College of Medical Veterinary and Life Sciences > School of Life Sciences
Journal Name:Biotechnic and Histochemistry
Publisher:Informa Healthcare
ISSN:1052-0295
ISSN (Online):1473-7760

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