Petrie, M.C. , Boyle, J.G. and McKay, G.A. (2015) Use of metformin in chronic kidney disease should continue to be based on common sense in the absence of an evidence base. Diabetic Medicine, 32(7), pp. 981-982. (doi: 10.1111/dme.12709) (PMID:25645049)
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Abstract
We read with interest the paper by Adam et al. [1] which argues for less restrictive guidelines for using metformin in stable chronic renal failure. While the authors’ assumption that the use of metformin in patients with advanced chronic kidney disease (CKD) may be safe and offer similar cardiovascular disease and mortality benefit is reasonable, their enthusiasm for less restrictive guidance in patients with an estimated GFR of <30 ml/min should be tempered by the lack of good evidence of benefit for this group [2,3].
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Boyle, Dr James and Petrie, Professor Mark and McKay, Dr Gerard |
Authors: | Petrie, M.C., Boyle, J.G., and McKay, G.A. |
College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
Journal Name: | Diabetic Medicine |
Publisher: | Wiley-Blackwell Publishing Ltd. |
ISSN: | 0742-3071 |
ISSN (Online): | 1464-5491 |
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