Plasmodium knowlesi: clinical presentation and laboratory diagnosis of the first human case in a Scottish traveler

Cordina, C. J., Culleton, R., Jones, B. L., Smith, C. C., MacConnachie, A. A., Coyne, M. J. and Alexander, C. L. (2014) Plasmodium knowlesi: clinical presentation and laboratory diagnosis of the first human case in a Scottish traveler. Journal of Travel Medicine, 21(5), pp. 357-360. (doi: 10.1111/jtm.12131) (PMID:24861374)

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Abstract

The first imported case of Plasmodium knowlesi in Scotland is described in a 33-year-old female with a travel history to Borneo. The patient ceased to take antimalarial prophylaxis after 4 days of her 10-day visit and presented with a history of fever, rigor, vomiting, and diarrhea after 13 days on her return to the UK. Malaria antigen detection using the Optimal-IT and Binax-NOW kits was negative. Unusual trophozoite-like structures were observed under microscopic examination and the identification of P. knowlesi performed by a nested polymerase chain reaction (PCR) gel-based approach was confirmed by using a PCR-sequencing assay.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Jones, Dr Brian and Alexander, Miss Claire
Authors: Cordina, C. J., Culleton, R., Jones, B. L., Smith, C. C., MacConnachie, A. A., Coyne, M. J., and Alexander, C. L.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Travel Medicine
Publisher:Wiley
ISSN:1195-1982
ISSN (Online):1708-8305

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