Wong, M. C.S., Wu, C. H.M., Wang, H. H. , Li, H. W., Hui, E. M.T., Lam, A. T., Chung, R. Y.N., Yip, B. H.K. and Morisky, D. E. (2015) Association between the 8-item Morisky medication adherence scale (MMAS-8) score and glycaemic control among Chinese diabetes patients. Journal of Clinical Pharmacology, 55(3), pp. 279-287. (doi: 10.1002/jcph.408) (PMID:25293349)
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Abstract
Adherence with oral hypoglycaemic agent is crucial to achieve optimal glycaemic control. The 8-item Morisky Medication Adherence Scale (MMAS-8) has been frequently used, yet the association between MMAS-8 score and glycaemic control among Chinese diabetes patients is largely unknown. Two general out-patient clinics were randomly selected in a district with socio-demographic characteristics representative of the entire Hong Kong population. A consecutive sample of adult type-2 diabetes patients currently taking oral hypoglycaemic agents was included. The glycaemic control was reflected by the level of hemoglobin A1c (HbA1c) taken within the previous 6 months. Factors associated with poor glycaemic control (HbA1c ≥ 7.0%) were evaluated by linear regression analysis. From 565 eligible Chinese patients with an average age of 63.2 years (SD 9.7) and male proportion of 46.5%, the average HbA1c was 7.1% (SD 1.1%), and 52.0% had poor glycaemic control. The proportion of poor medication adherence (MMAS-8 ≤ 6) was 32.2%. After controlling for socio-demographics, lifestyle, medication use, and health characteristics, the MMAS-8 score was correlated with better glycaemic control (beta −0.095; 95%CI −0.164 to −0.026, P = .007). The MMAS-8 score had a weak and negative correlation with HbA1c level. The instrument should be applied with caution when predicting glycaemic control in clinical practice.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Wang, Professor Haoxiang |
| Authors: | Wong, M. C.S., Wu, C. H.M., Wang, H. H., Li, H. W., Hui, E. M.T., Lam, A. T., Chung, R. Y.N., Yip, B. H.K., and Morisky, D. E. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care |
| Journal Name: | Journal of Clinical Pharmacology |
| Publisher: | Wiley |
| ISSN: | 0091-2700 |
| ISSN (Online): | 1552-4604 |
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