Regulation of stem cell fate by nanomaterial substrates

Mashinchian, O., Turner, L.-A., Dalby, M. J. , Laurent, S., Shokrgozar, M. A., Bonakdar, S., Imani, M. and Mahmoudi, M. (2015) Regulation of stem cell fate by nanomaterial substrates. Nanomedicine, 10(5), pp. 829-847. (doi:10.2217/nnm.14.225) (PMID:25816883)

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Abstract

Stem cells are increasingly studied because of their potential to underpin a range of novel therapies, including regenerative strategies, cell type-specific therapy and tissue repair, among others. Bionanomaterials can mimic the stem cell environment and modulate stem cell differentiation and proliferation. New advances in these fields are presented in this review. This work highlights the importance of topography and elasticity of the nano-/micro-environment, or niche, for the initiation and induction of stem cell differentiation and proliferation.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Dalby, Professor Matthew and Turner, Dr Lesley-Anne
Authors: Mashinchian, O., Turner, L.-A., Dalby, M. J., Laurent, S., Shokrgozar, M. A., Bonakdar, S., Imani, M., and Mahmoudi, M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
Journal Name:Nanomedicine
Publisher:Future Medicine Ltd.
ISSN:1743-5889
ISSN (Online):1748-6963

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