Panton-valentine leukocidin positive staphylococcal aureus infections of the head and neck: case series and brief review of literature

Hanratty, J., Changez, H., Smith, A. and Wales, C. (2015) Panton-valentine leukocidin positive staphylococcal aureus infections of the head and neck: case series and brief review of literature. Journal of Oral and Maxillofacial Surgery, 73(4), pp. 666-670. (doi:10.1016/j.joms.2014.10.004) (PMID:25544295)

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Abstract

Panton-valentine leukocidin (PVL) is a pore-forming cytotoxin produced by some clones of Staphylococcus aureus that is associated with infections ranging from uncomplicated skin and soft tissue infections to life-threatening necrotizing pneumonia. PVL S aureus–associated maxillofacial infections are rarely reported; therefore, a high degree of clinical suspicion is warranted and close liaison with microbiologists and appropriate samples are required for optimal management. This report discusses the management and learning points from 3 such cases managed by the Greater Glasgow and Clyde National Health Service maxillofacial surgical teams.<p></p> Panton-Valentine leukocidin (PVL) is a virulence factor produced by some clones of Staphylococcus aureus. These isolates are associated with infections that range from uncomplicated skin and soft tissue infections to life-threatening entities such as necrotizing pneumonia. 1 and 2 This report presents a case series of 3 PVL-positive community-acquired methicillin-sensitive S aureus (PVL CA-MSSA) infections treated by the maxillofacial team at the Southern General Hospital (Glasgow, United Kingdom) over a 6-month period in 2013 and discusses the clinical implications of PVL S aureus infections in this patient group.<p></p>

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Smith, Professor Andrew
Authors: Hanratty, J., Changez, H., Smith, A., and Wales, C.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
Journal Name:Journal of Oral and Maxillofacial Surgery
Publisher:Elsevier
ISSN:0278-2391
ISSN (Online):1531-5053

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