Shell proteome of rhynchonelliform brachiopods

Immel, F., Gaspard, D., Marie, A., Guichard, N., Cusack, M. and Marin, F. (2015) Shell proteome of rhynchonelliform brachiopods. Journal of Structural Biology, 190(3), pp. 360-366. (doi: 10.1016/j.jsb.2015.04.001) (PMID:25896726)

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Abstract

Brachiopods are a phylum of marine invertebrates that have an external bivalved shell to protect their living tissues. With few exceptions, this biomineralized structure is composed of calcite, mixed together with a minor organic fraction, comprising secreted proteins that become occluded in the shell structure, once formed. This organic matrix is thought to display several functions, in particular, to control mineral deposition and to regulate crystallite shapes. Thus, identifying the primary structure of matrix proteins is a prerequisite for generating bioinspired materials with tailored properties. In this study, we employed a proteomic approach to identify numerous peptides that constitute the shell proteins, in three rhynchonellid brachiopods from different localities. Our results suggest that the shell protein repertoires identified thus far, differ from that of better known calcifying metazoans, such as molluscs.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cusack, Professor Maggie
Authors: Immel, F., Gaspard, D., Marie, A., Guichard, N., Cusack, M., and Marin, F.
College/School:College of Science and Engineering > School of Geographical and Earth Sciences
Journal Name:Journal of Structural Biology
Publisher:Elsevier Inc.
ISSN:1047-8477
ISSN (Online):1095-8657

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
452471Understanding polymorph production and control in calcite/aragonite biomineralsAndrew FreerBiotechnology and Biological Sciences Research Council (BBSRC)BB/E025110/1CHEM - CHEMISTRY