Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008

Jones, N.R.V., Fischbacher, C.M., Guthrie, B., Leese, G., Lindsay, R.S. , McKnight, J.A., Pearson, D., Philip, S., Sattar, N. and Wild, S.H. (2014) Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008. Diabetic Medicine, 31(6), pp. 640-646. (doi:10.1111/dme.12409) (PMID:24533646) (PMCID:PMC4232871)

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Abstract

Aim To describe characteristics associated with statin prescribing for the primary prevention of cardiovascular disease in people with newly diagnosed diabetes.<p></p> Methods Data from the Scottish Care Information—Diabetes Collaboration data set for 2006–2008 were used. This data set contains socio-demographic and prescribing data for over 99% of people with diagnosed diabetes in Scotland. Analyses were conducted on people aged over 40 years diagnosed with Type 1 or Type 2 diabetes between 2006 and 2008 with complete data and no previous history of cardiovascular or statin prescription. Logistic regression was used to calculate odds ratios for statin prescription in the 2 years following diagnosis of diabetes.<p></p> Results There were 7157 men and 5601 women who met the inclusion criteria, 68% of whom had a statin prescription recorded in the 2 years following diagnosis of diabetes. The proportions receiving statins were lower above 65 years of age in men and 75 years of age in women. People with Type 1 diabetes had lower odds of receiving statins than people with Type 2 diabetes [odds ratio (95% CI) 0.42 (0.29–0.61) for men and 0.48 (0.28–0.81) for women, after adjustment for age, BMI, smoking status, cholesterol level and deprivation]. Higher total cholesterol, BMI and being a current smoker were associated with greater odds of statin prescription.<p></p> Conclusion Approximately one third of the study population had no record of statin prescription during the 2 years after diagnosis of diabetes. Cardiovascular disease risk reduction opportunities may be missed in some of these people.<p></p>

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Lindsay, Dr Robert and Sattar, Professor Naveed
Authors: Jones, N.R.V., Fischbacher, C.M., Guthrie, B., Leese, G., Lindsay, R.S., McKnight, J.A., Pearson, D., Philip, S., Sattar, N., and Wild, S.H.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Diabetic Medicine
Publisher:Wiley
ISSN:0742-3071
ISSN (Online):1464-5491
Copyright Holders:Copyright © 2014 The Authors
First Published:First published in Diabetic Medicine 31(6):640-646
Publisher Policy:Reproduced under a Creative Commons License

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